PDB
8Y73
Resolution
2.8 Å
Released
Aug. 6, 2025
Receptor
μ
Class
A
Species
Homo sapiens
Ligands
MPAM-15
DAMGO
Function
PAM
Agonist
Reference
—
MPAM-15 DAMGO

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
MPAM-15 L118 2.52x52 TM2 hydrophobic
MPAM-15 I144 3.27x27 TM3 hydrophobic
DAMGO V145 3.28x28 TM3 hydrophobic
DAMGO I146 3.29x29 TM3 hydrophobic
MPAM-15 I148 3.31x31 TM3 hydrophobic
MPAM-15 Y151 3.34x34 TM3 hydrophobic
MPAM-15 N152 3.35x35 TM3 Van der Waals
MPAM-15 N152 3.35x35 TM3 polar (hydrogen bond)
DAMGO M153 3.36x36 TM3 hydrophobic
MPAM-15 W194 4.50x50 TM4 Van der Waals
MPAM-15 W194 4.50x50 TM4 hydrophobic
MPAM-15 S198 4.54x54 TM4 Van der Waals
MPAM-15 G201 4.57x57 TM4 Van der Waals
MPAM-15 L202 4.58x58 TM4 hydrophobic
MPAM-15 L202 4.58x58 TM4 Van der Waals
MPAM-15 M205 4.61x61 TM4 hydrophobic
MPAM-15 M205 4.61x61 TM4 Van der Waals
DAMGO V238 5.42x43 TM5 hydrophobic
DAMGO V302 6.55x55 TM6 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A A P T N A S N C T D A L A Y S S C S P A P S P G S W V N L S H L D G N L S D P C G P N R T D L G G R D S L C P P T G S P S N-termC-term P T S S N I E Q Q N S T R I R Q N T R D H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I I N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
Helix box plot — Download: PNG | SVG F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I I N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7

GPCRdb(A)
GPCRdb(A)
μ receptor
TM2
2x52 2.52x52 L118
TM3
3x27 3.27x27 I144
3x28 3.28x28 V145
3x29 3.29x29 I146
3x31 3.31x31 I148
3x34 3.34x34 Y151
3x35 3.35x35 N152
3x36 3.36x36 M153
TM4
4x50 4.50x50 W194
4x54 4.54x54 S198
4x57 4.57x57 G201
4x58 4.58x58 L202
4x61 4.61x61 M205
TM5
5x43 5.42x43 V238
TM6
6x55 6.55x55 V302