Structure information

succinate receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YKV

SPECIES

Homo sapiens

RESOLUTION

2.480

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

May 29, 2024

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Sucnr1-IN-2 L79 2.60x60 TM2 hydrophobic
Sucnr1-IN-2 Y83 2.64x64 TM2 polar (hydrogen bond)
Sucnr1-IN-2 Y83 2.64x64 TM2 Van der Waals
Sucnr1-IN-2 G86 ECL1 Van der Waals
Sucnr1-IN-2 G86 ECL1 polar (hydrogen bond with backbone)
Sucnr1-IN-2 W88 23.50x50 ECL1 Van der Waals
Sucnr1-IN-2 W88 23.50x50 ECL1 hydrophobic
Sucnr1-IN-2 N98 3.28x28 TM3 Van der Waals
Sucnr1-IN-2 R99 3.29x29 TM3 polar (charge-assisted hydrogen bond)
Sucnr1-IN-2 L102 3.32x32 TM3 hydrophobic
Sucnr1-IN-2 L102 3.32x32 TM3 Van der Waals
Sucnr1-IN-2 H103 3.33x33 TM3 Van der Waals
Sucnr1-IN-2 H103 3.33x33 TM3 polar (hydrogen bond)
Sucnr1-IN-2 D174 45.52x52 ECL2 polar (hydrogen bond with backbone)
Sucnr1-IN-2 D174 45.52x52 ECL2 Van der Waals
Sucnr1-IN-2 F175 ECL2 Van der Waals
Sucnr1-IN-2 R281 7.39x38 TM7 polar (charge-assisted hydrogen bond)

Ligands

Sucnr1-IN-2

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Residue Diagrams

T N G L V G V V F E I G Y F I S L Y Y K 1 F N L S V S D L A F L C T L P M L I R S 2 F T L F L I S T Y L N A H L V Y R N S I 3 A I L I S L A I W V L V T L E L L P I 4 Y F F C M V F L P I L F G L L T L C M S Y 5 I M A V V I F S V L F T P Y H V M R N V 6 V P N I V S N L F A L P R T V I Y F S 7
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ICL1 K N W ICL1ECL1 G N W I Y ECL1ICL2 P F R E H L L Q ICL2ECL2 I T D N G T T C N D F A S S G ECL2ICL3 T A L P ICL3ECL3 S W K Q ECL3N-term M L G I M A W N A T N-termC-term T S F S R W A H E L L L S F R E K C-term C K N W L A A E A A L E K Y Y L S I F Y G I E F V V G V L G N T I V V Y G Y I F S L N S S N I Y L F N L S V S D L A F L C T L P M L I R S Y A N G D V L C I S N R Y V L H A N L Y T S I L F L T F I S I D R Y L I I K Y K K E F A I L I S L A I W V L V T L E L L P I L P L I N P V D P N Y N L I Y S M C L T L L G F L I P L F V M C F F Y Y K I A L F L K Q R N R Q V A L E K P L N L V I M A V V I F S V L F T P Y H V M R N V R I A S R L G Y Q C T Q V V I N S F Y I V T R P L A F L N S V I N P V F Y F L L G D H L M N N F K F R D M Q L R H S L
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Residue Table


GPCRdb(A)
GPCRdb(A)
succinate receptor
TM2
2x60 2.60x60 L79
2x64 2.64x64 Y83
ECL1
23x50 23.50x50 W88
TM3
3x28 3.28x28 N98
3x29 3.29x29 R99
3x32 3.32x32 L102
3x33 3.33x33 H103
ECL2
45x52 45.52x52 D174
TM7
7x38 7.39x38 R281