Structure information

succinate receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YKV

SPECIES

Homo sapiens

RESOLUTION

2.480

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

May 29, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
CHEMBL5430997 L79 2.60x60 TM2 hydrophobic
CHEMBL5430997 Y83 2.64x64 TM2 polar (hydrogen bond)
CHEMBL5430997 Y83 2.64x64 TM2 Van der Waals
CHEMBL5430997 G86 ECL1 Van der Waals
CHEMBL5430997 G86 ECL1 polar (hydrogen bond with backbone)
CHEMBL5430997 W88 23.50x50 ECL1 Van der Waals
CHEMBL5430997 W88 23.50x50 ECL1 hydrophobic
CHEMBL5430997 N98 3.28x28 TM3 Van der Waals
CHEMBL5430997 R99 3.29x29 TM3 polar (charge-assisted hydrogen bond)
CHEMBL5430997 L102 3.32x32 TM3 hydrophobic
CHEMBL5430997 L102 3.32x32 TM3 Van der Waals
CHEMBL5430997 H103 3.33x33 TM3 Van der Waals
CHEMBL5430997 H103 3.33x33 TM3 polar (hydrogen bond)
CHEMBL5430997 D174 45.52x52 ECL2 polar (hydrogen bond with backbone)
CHEMBL5430997 D174 45.52x52 ECL2 Van der Waals
CHEMBL5430997 F175 ECL2 Van der Waals
CHEMBL5430997 R281 7.39x38 TM7 polar (charge-assisted hydrogen bond)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 17 of 17 entries

Ligands

CHEMBL5430997

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Residue Diagrams

T N G L V G V V F E I G Y F I S L Y Y K 1 F N L S V S D L A F L C T L P M L I R S 2 F T L F L I S T Y L N A H L V Y R N S I 3 A I L I S L A I W V L V T L E L L P I 4 Y F F C M V F L P I L F G L L T L C M S Y 5 I M A V V I F S V L F T P Y H V M R N V 6 V P N I V S N L F A L P R T V I Y F S 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term C K N W L A A E A A L E K Y Y L S I F Y G I E F V V G V L G N T I V V Y G Y I F S L N S S N I Y L F N L S V S D L A F L C T L P M L I R S Y A N G D V L C I S N R Y V L H A N L Y T S I L F L T F I S I D R Y L I I K Y K K E F A I L I S L A I W V L V T L E L L P I L P L I N P V D P N Y N L I Y S M C L T L L G F L I P L F V M C F F Y Y K I A L F L K Q R N R Q V A L E K P L N L V I M A V V I F S V L F T P Y H V M R N V R I A S R L G Y Q C T Q V V I N S F Y I V T R P L A F L N S V I N P V F Y F L L G D H L M N N F K F R D M Q L R H S L
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Residue Table


GPCRdb(A)
GPCRdb(A)
succinate receptor
TM2
2x60 2.60x60 L79
2x64 2.64x64 Y83
ECL1
23x50 23.50x50 W88
TM3
3x28 3.28x28 N98
3x29 3.29x29 R99
3x32 3.32x32 L102
3x33 3.33x33 H103
ECL2
45x52 45.52x52 D174
TM7
7x38 7.39x38 R281