Structure information

MCH1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YNS

SPECIES

Homo sapiens

RESOLUTION

3.330

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

Dec. 18, 2024
|

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
CHEMBL242004 F116 1.39x39 TM1 aromatic (face-to-face)
CHEMBL242004 F161 2.53x53 TM2 hydrophobic
CHEMBL242004 M165 2.57x57 TM2 polar (hydrogen bond)
CHEMBL242004 M168 2.60x60 TM2 hydrophobic
CHEMBL242004 M168 2.60x60 TM2 Van der Waals
CHEMBL242004 I169 2.61x61 TM2 Van der Waals
CHEMBL242004 D192 3.32x32 TM3 polar (charge-assisted hydrogen bond)
CHEMBL242004 S195 3.35x35 TM3 Van der Waals
CHEMBL242004 Q196 3.36x36 TM3 Van der Waals
CHEMBL242004 F427 6.44x44 TM6 hydrophobic
CHEMBL242004 F427 6.44x44 TM6 Van der Waals
CHEMBL242004 W431 6.48x48 TM6 Van der Waals
CHEMBL242004 W431 6.48x48 TM6 aromatic (face-to-face)
CHEMBL242004 W431 6.48x48 TM6 polar (hydrogen bond)
CHEMBL242004 Y434 6.51x51 TM6 Van der Waals
CHEMBL242004 Y434 6.51x51 TM6 hydrophobic
CHEMBL242004 Y435 6.52x52 TM6 Van der Waals
CHEMBL242004 Y455 7.35x34 TM7 Van der Waals
CHEMBL242004 I459 7.39x38 TM7 hydrophobic
CHEMBL242004 I459 7.39x38 TM7 Van der Waals
CHEMBL242004 Y463 7.43x42 TM7 Van der Waals
CHEMBL242004 Y463 7.43x42 TM7 aromatic (edge-to-face)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 22 of 22 entries

Ligands

CHEMBL242004

3D interaction viewer Download PDB file
  |  

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

S N G I I G L L C I T G F V S P M I I N 1 I N L S V V D L L F L L G M P F M I H Q 2 A T L I Y T S T F Q S N A D M A T I L T 3 A T L V I C L L W A L S F I S I T P V 4 Y A A T I V V F P L A F A L F F Q Y L T F 5 I A I C L V F F V C W A P Y Y V L Q L T 6 F P N L C S N A Y G L S I A A N Y L Y 7
Download: PNG | SVG
ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term S Y I N I I M P S V F G T I C L L G I I G N S T V I F A V V K K S N V P D I F I I N L S V V D L L F L L G M P F M I H Q L M G G E T M C T L I T A M D A N S Q F T S T Y I L T A M A I D R Y L A T V H K P S V A T L V I C L L W A L S F I S I T P V W L Y A P D T D L Y W F T L Y Q F F L A F A L P F V V I T A A Y V R I L Q R M Q R S I R L R T K R V T R T A I A I C L V F F V C W A P Y Y V L Q L T Q L S I L T F V Y L Y N A A I S L G Y A N S C L N P F V Y I V L C E T L V L F R K R S V K
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
MCH1 receptor
TM1
1x39 1.39x39 F116
TM2
2x53 2.53x53 F161
2x57 2.57x57 M165
2x60 2.60x60 M168
2x61 2.61x61 I169
TM3
3x32 3.32x32 D192
3x35 3.35x35 S195
3x36 3.36x36 Q196
TM6
6x44 6.44x44 F334
6x48 6.48x48 W338
6x51 6.51x51 Y341
6x52 6.52x52 Y342
TM7
7x34 7.35x34 Y362
7x38 7.39x38 I366
7x42 7.43x42 Y370