Structure information

MRGPRX4

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8YRG

SPECIES

Homo sapiens

RESOLUTION

3.140

PREFERRED CHAIN

R

REFERENCE

PUBLICATION DATE

May 22, 2024

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
Fospropofol R82 2.60x60 TM2 polar (charge-assisted hydrogen bond)
Fospropofol R86 2.64x64 TM2 polar (charge-assisted hydrogen bond)
Fospropofol H92 3.22x22 TM3 Van der Waals
Fospropofol R95 3.25x25 TM3 Van der Waals
Fospropofol K96 3.26x26 TM3 Van der Waals
Fospropofol V99 3.29x29 TM3 hydrophobic
Fospropofol V99 3.29x29 TM3 Van der Waals
Fospropofol Y250 7.31x30 TM7 aromatic (edge-to-face)
Fospropofol Y250 7.31x30 TM7 polar (hydrogen bond)
Fospropofol Y250 7.31x30 TM7 polar (hydrogen bond)
Fospropofol Y254 7.35x34 TM7 Van der Waals
Fospropofol Y254 7.35x34 TM7 hydrophobic

Ligands

Fospropofol

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

A N G T L G V L S I I C T L V T F S L T 1 L N L A A A D F L F L S F Q I I R L P L 2 A S L M S L G T F Y P F T M V S V L I K 3 S A V V C V L L W G L S L L F S M L E W 4 S S V C L V V C L F I L W A V P I F D S 5 L L T V L V F L L C G L P F G I L G A L 6 I P N A S S N L S S L S M C V L Y V H 7
Download: PNG | SVG
ICL1 R R ICL1ECL1 I N I ECL1ICL2 P I W Y R C R R P T ICL2ECL2 D F L F S G A ECL2ICL3 G S R K M ICL3ECL3 I Y R M H L N L E ECL3N-term M D P T V P V F G T K L T P I N G R E E T P C Y N N-termC-term Q R Q N R Q N L K L V L Q R A L Q D K P E V D K G E G Q L P E E S L E L S G S R L G P C-term Q T L S F T V L T C I I S L V G L T G N A V V L W L L G Y R M N A V S I Y I L N L A A A D F L F L S F Q I I R L P L R L S H L I R K I L V S V M T F P Y F T G L S M L S A I S T E R C L S V L W H L S A V V C V L L W G L S L L F S M L E W R F C D S S W C E T S D F I P V A W L I F L C V V L C V S S L V L L V R I L C P L T R L Y V T I L L T V L V F L L C G L P F G I L G A L V L Y C H V Y L V C M S L S S L N S S A N P I I Y F F V G S F R
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
MRGPRX4
TM2
2x60 2.60x60 R82
2x64 2.64x64 R86
TM3
3x22 3.22x22 H92
3x25 3.25x25 R95
3x26 3.26x26 K96
3x29 3.29x29 V99
TM7
7x30 7.31x30 Y250
7x34 7.35x34 Y254