Structure information

CB1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

9B9Y

SPECIES

Homo sapiens

RESOLUTION

3.500

PREFERRED CHAIN

R

REFERENCE

10.1038/S41467-024-54206-0

PUBLICATION DATE

Nov. 20, 2024
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
taranabant F102 N-term hydrophobic
taranabant M103 N-term hydrophobic
taranabant F108 N-term hydrophobic
taranabant G166 2.53x53 TM2 Van der Waals
taranabant G166 2.53x53 TM2 polar (hydrogen bond with backbone)
taranabant F170 2.57x57 TM2 Van der Waals
taranabant F170 2.57x57 TM2 aromatic (edge-to-face)
taranabant V196 3.32x32 TM3 hydrophobic
taranabant V196 3.32x32 TM3 Van der Waals
taranabant F268 ECL2 Van der Waals
taranabant F268 ECL2 hydrophobic
taranabant L359 6.51x51 TM6 hydrophobic
taranabant L359 6.51x51 TM6 Van der Waals
taranabant F379 7.35x34 TM7 Van der Waals
taranabant A380 7.36x35 TM7 Van der Waals
taranabant S383 7.39x38 TM7 polar (hydrogen bond)
taranabant M384 7.40x39 TM7 polar (hydrogen bond)
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 17 of 17 entries

Ligands

taranabant

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Residue Diagrams

L N E L V T F T G L T L S L V A I A L Q 1 G S L A V A D L L G S V I F V Y S F I D 2 L F L S G V S A T F S A T V G G L K F L 3 A V V A F C L M W T I A I V I A V L P L 4 Y A Y V I F L L L V S T V G I W F M L Y 5 V L I L V V L I I C W G P L L A I M V Y 6 I P N V T S N L L C L M S C F A F V T 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term N P S Q Q L A I A V L S L T L G T F T V L E N L L V L C V I L H S R P S Y H F I G S L A V A D L L G S V I F V Y S F I D F H V S R N V F L F K L G G V T A S F T A S V G S L F L T A I D R Y I S I H R T R P K A V V A F C L M W T I A I V I A V L P L L G D E T Y L M F W I G V T S V L L L F I V Y A Y M Y I L W K A H S H A V R M I Q R G P D Q A R M D I R L A K T L V L I L V V L I I C W G P L L A I M V Y D V F G N K L I K T V F A F C S M L C L L N S T V N P I I Y A L R S K D F R S L R H A M F P
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Residue Table


GPCRdb(A)
GPCRdb(A)
CB1 receptor
TM2
2x53 2.53x53 G166
2x57 2.57x57 F170
TM3
3x32 3.32x32 V196
TM6
6x51 6.51x51 L359
TM7
7x34 7.35x34 F379
7x35 7.36x35 A380
7x38 7.39x38 S383
7x39 7.40x39 M384