PDB
9XDR
Resolution
2.6 Å
Released
July 8, 2026
Receptor
κ
Class
A
Species
Homo sapiens
Ligands
BMS-986187
asimadoline
Function
Ago-PAM
Agonist
Reference
—
BMS-986187 asimadoline

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
BMS-986187 I133 3.27x27 TM3 hydrophobic
asimadoline I135 3.29x29 TM3 hydrophobic
BMS-986187 I137 3.31x31 TM3 hydrophobic
asimadoline D138 3.32x32 TM3 polar (charge-assisted hydrogen bond)
asimadoline Y139 3.33x33 TM3 hydrophobic
asimadoline Y139 3.33x33 TM3 Van der Waals
BMS-986187 Y140 3.34x34 TM3 hydrophobic
BMS-986187 I194 4.61x61 TM4 hydrophobic
asimadoline L212 45.52x52 ECL2 Van der Waals
asimadoline W287 6.48x48 TM6 hydrophobic
asimadoline W287 6.48x48 TM6 Van der Waals
asimadoline I290 6.51x51 TM6 hydrophobic
asimadoline I290 6.51x51 TM6 Van der Waals
asimadoline H291 6.52x52 TM6 Van der Waals
asimadoline I316 7.39x38 TM7 Van der Waals
asimadoline I316 7.39x38 TM7 polar (hydrogen bond with backbone)
asimadoline G319 7.42x41 TM7 Van der Waals
asimadoline Y320 7.43x42 TM7 Van der Waals
asimadoline Y320 7.43x42 TM7 hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 T K M K ICL1ECL1 S W P F ECL1ICL2 P V K A L D F R ICL2ECL2 G T K V R E D V D V I E C S L Q F P D D ECL2ICL3 R L L S G ICL3ECL3 S T S H ECL3N-term M D S P I Q I F R G E P G P T C A P S A C L P P N S S A W F P G W A E P D S N G S A G S E D A Q L E P A H I S P N-termC-term P L K M R M E R Q S T S R V R N T V Q D P A Y L R D I D G M N K P V C-term A I P V I I T A V Y S V V F V V G L V G N S L V M F V I I R Y T A T N I Y I F N L A L A D A L V T T T M P F Q S T V Y L M N G D V L C K I V I S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P L K A K I I N I C I W L L S S S V G I S A I V L G D Y S W W D L F M K I C V F I F A F V I P V L I I I V C Y T L M I L R L K S V S R E K D R N L R R I T R L V L V V V A V F V V C W T P I H I F I L V E A L G S T A A L S S Y Y F C I A L G Y T N S S L N P I L Y A F L D E N F R D F K R C F C F
Helix box plot — Download: PNG | SVG S N G V L G V V F V V S Y V A T I I V P 1 F N L A L A D A L V T T T M P F Q S T V 2 M T L T F I S T F M N Y Y D I S I V I K 3 A K I I N I C I W L L S S S V G I S A I 4 Y C V I I I L V P I V F A F I F V C I K M 5 L V V V A V F V V C W T P I H I F I L V 6 I P N L S S N T Y G L A I C F Y Y S S 7

GPCRdb(A)
GPCRdb(A)
κ receptor
TM3
3x27 3.27x27 I133
3x29 3.29x29 I135
3x31 3.31x31 I137
3x32 3.32x32 D138
3x33 3.33x33 Y139
3x34 3.34x34 Y140
TM4
4x61 4.61x61 I194
ECL2
45x52 45.52x52 L212
TM6
6x48 6.48x48 W287
6x51 6.51x51 I290
6x52 6.52x52 H291
TM7
7x38 7.39x38 I316
7x41 7.42x41 G319
7x42 7.43x42 Y320