CHEMBL246439


SMILES Cc1[nH]c2ccccc2c1CN1CCC(O)(c2ccc(Cl)cc2)CC1
InChIKey CMIREZHKYCLJMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.52 5.52 5.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.81 7.81 7.81 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.7 7.7 7.7 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.67 8.67 8.67 ChEMBL