CHEMBL246855


SMILES CCCCCCn1cc(CN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc21
InChIKey KHNRAYBLMYKIRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 424.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.05 5.05 5.05 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.31 6.31 6.31 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.18 6.18 6.18 ChEMBL
D2 DRD2 Human Dopamine A pEC50 6.78 6.78 6.78 ChEMBL