CHEMBL29410


SMILES COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN2CCCCC2C1
InChIKey XGBXESVSCSHHQI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 505.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.4 5.4 5.4 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.7 5.7 5.7 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database