Compound 30 [Pmid: 21757343]

Chemical Properties

SMILES Clc1cccc(c1)c1ncc(c(c1)C)[C@H]1CCCN1C(=O)c1nccs1
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 383.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey GCSDBTCZHROCLZ-GOSISDBHSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.92 7.92 7.92 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.77 7.77 7.77 Guide to Pharmacology
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.92 7.92 7.92 Guide to Pharmacology
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.92 7.92 7.92 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.77 7.77 7.77 ChEMBL