CHEMBL299253


SMILES O=C1CC2(C=CN1CCN1CCN(c3ccccc3Cl)CC1)CCCC2
InChIKey XOSAFCKSDPJGTM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.08 9.08 9.08 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.69 7.69 7.69 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.27 7.27 7.27 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.36 7.37 7.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database