CHEMBL300571


SMILES Oc1ccc2c(c1)O[C@@H](CNCc1ccccc1)CO2
InChIKey DYWYWIOQKKRAST-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 271.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.78 7.78 7.78 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.24 8.84 9.46 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.96 8.96 8.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.14 8.14 8.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database