CHEMBL253814


SMILES CC1(C)CCc2nc(C#Cc3ccccc3)ccc2C1=O
InChIKey GXHZJFOEDFUGMK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 275.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.29 7.29 7.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.64 7.64 7.64 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.63 7.67 7.7 ChEMBL