CHEMBL299691


SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccccc2F)CC1
InChIKey CYDFRMLIERPUGG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 373.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.28 8.28 8.28 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.17 7.19 7.2 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.08 9.08 9.08 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.2 6.2 6.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.49 7.8 8.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database