CHEMBL299879


SMILES O=[N+]([O-])c1ccccc1S(=O)(=O)NC[C@H]1CC[C@H](CNCC2CCc3ccccc3C2)CC1
InChIKey ISSSVYKMIIAPTH-YGQOYYDZSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y1 NPY1R Rat Neuropeptide Y A pKi 4.66 4.66 4.66 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.0 7.0 7.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.2 7.2 7.2 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 4.79 4.79 4.79 ChEMBL
Y5 NPY5R Human Neuropeptide Y A pKi 8.1 8.1 8.1 ChEMBL
Y5 NPY5R Rat Neuropeptide Y A pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 5.0 5.0 5.0 ChEMBL