CHEMBL304391


SMILES CNC(=O)c1ccc(CN2CCN(CC(=O)N3c4ccccc4C(=O)Nc4cccnc43)CC2)cc1
InChIKey ZJSOFJRIJVTWTE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 5.53 5.53 5.53 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.4 5.4 5.4 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 5.58 5.58 5.58 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database