CHEMBL305403


SMILES NCCNC(=O)c1ccc(CN2CCN(CC(=O)N3c4ccccc4C(=O)Nc4cccnc43)CC2)cc1
InChIKey BMFWWGQJIXNFNW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 513.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 5.98 5.98 5.98 ChEMBL
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 5.44 5.44 5.44 ChEMBL
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 6.02 6.02 6.02 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database