GproteinDb

CHEMBL1160787

Agent/drug
Bioactivity

CHEMBL1160787

SMILES	Oc1cc2c(c(Cl)c1O)CCNC[C@@H]2c1ccccc1
InChIKey	GHWJEDJMOVUXEC-CYBMUJFWSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	1
Molecular weight (Da)	289.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7JV5 7LJC

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pKi	7.52	7.52	7.52	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKd	4.89	5.21	5.52	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	5.10	5.10	5.10	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₁	DRD1	Human	Dopamine	A	pEC50	7.88	8.29	8.70	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL1160787

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb
Structure pdb	7JV5 7LJC

Compound is not listed as a drug.