Ligand Data

Ligand

id 102423
Name CHEMBL300792
SMILES Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4C5CCC4CC5)cc3c2CCN(CCCCc2ccncc2)CC(C)C)c1
InChIKey OOAJRTTYQBLLKA-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight 618.4


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A (Rhodopsin) 8.2 8.2 8.2
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A (Rhodopsin) 300 300 300