Ligand Data
Ligand
| Name | CHEMBL300792 |
| SMILES | Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4C5CCC4CC5)cc3c2CCN(CCCCc2ccncc2)CC(C)C)c1 |
| InChIKey | OOAJRTTYQBLLKA-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 13 |
| Molecular weight | 618.4 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| GnRH1 | GNRHR | Rat | Gonadotrophin-releasing hormone | A (Rhodopsin) | 8.2 | 8.2 | 8.2 | |||
| GnRH1 | GNRHR | Human | Gonadotrophin-releasing hormone | A (Rhodopsin) | 300 | 300 | 300 | |||