CHEMBL306478


SMILES O=C(c1ccc(F)cc1)C1CCN(CCc2cccc(I)c2)CC1
InChIKey QJFCDRQWMDZIGI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 437.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.06 8.06 8.06 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.29 7.29 7.29 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.31 7.31 7.31 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.78 7.78 7.78 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.29 9.29 9.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database