CHEMBL258332


SMILES O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)Cc2cccc(Cl)c2)cc1
InChIKey CGEIKXUPHBHCKZ-BPFVEMAFSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 413.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pKi 6.0 6.0 6.0 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 10.7 10.7 10.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 6.6 6.6 6.6 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 10.52 10.52 10.52 ChEMBL