CHEMBL305362


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(-c2ccccc2)cc1
InChIKey JNGNQZWCWJWYDP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 481.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.94 9.0 9.05 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.55 6.55 6.55 ChEMBL
D3 DRD3 Human Dopamine A pKd 8.95 8.95 8.95 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database