CHEMBL3084634


SMILES Clc1ccccc1C(c1ccccc1Cl)N1[C@H]2CC[C@@H]1C[C@H](c1ccccn1)C2
InChIKey TYLQNPVGILBSQQ-REPLKXPHSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 422.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.3 8.3 8.3 ChEMBL
δ OPRD Human Opioid A pKi 4.94 4.94 4.94 ChEMBL
κ OPRK Human Opioid A pKi 6.29 6.29 6.29 ChEMBL
μ OPRM Human Opioid A pKi 5.97 5.97 5.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.55 7.55 7.55 ChEMBL
μ OPRM Human Opioid A pEC50 5.66 5.66 5.66 ChEMBL