CHEMBL308347


SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C#N)c3c2C1
InChIKey ODCNQSRYNGLVNW-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.35 7.35 7.35 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.17 8.17 8.17 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.38 7.02 7.66 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.57 8.84 9.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database