CHEMBL266393


SMILES COc1nsnc1N1CCN(C[C@@H](Cc2cccnc2)NC(=O)C2(C)CCCCC2)CC1
InChIKey SWKBPFACSXLZFM-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 458.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 5.45 5.45 5.45 ChEMBL
D4 DRD4 Human Dopamine A pIC50 5.96 5.96 5.96 ChEMBL
D3 DRD3 Human Dopamine A pIC50 6.31 6.31 6.31 ChEMBL