CHEMBL309021


SMILES COc1ccc(C(=O)Nc2ccc(-c3ccncc3)cc2)cc1CCCN(C)C
InChIKey OARBZUBLNNFTMQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Guinea pig 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.15 7.48 7.81 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 4.7 4.7 4.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database