CHEMBL26929


SMILES COc1ccccc1N1CCN(CCCC2CCCc3c(OC)cccc32)CC1
InChIKey INGWKGCHJJYQIB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 394.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 8.15 8.15 8.15 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.7 7.74 7.75 ChEMBL
D4 DRD4 Human Dopamine A pIC50 7.22 7.22 7.22 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 9.11 9.21 9.49 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.7 7.7 7.7 ChEMBL