SRIF-28
| SMILES | None |
| InChIKey | GGYTXJNZMFRSLX-DFTNLTQTSA-N |
| Sequence | SANSNPAMAPRERKAGCKNFFWKTFTSC |
Chemical properties
| Hydrogen bond acceptors | None |
| Hydrogen bond donors | None |
| Rotatable bonds | None |
| Molecular weight (Da) |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Endogenous |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| SST1 | SSR1 | Human | Somatostatin | A | pKi | 8.6 | 9.0 | 9.4 | Guide to Pharmacology |
| SST2 | SSR2 | Human | Somatostatin | A | pKi | 8.4 | 9.3 | 10.2 | Guide to Pharmacology |
| SST3 | SSR3 | Human | Somatostatin | A | pKi | 8.1 | 9.0 | 9.9 | Guide to Pharmacology |
| SST4 | SSR4 | Human | Somatostatin | A | pKi | 8.1 | 8.65 | 9.2 | Guide to Pharmacology |
| SST5 | SSR5 | Human | Somatostatin | A | pKi | 9.2 | 9.75 | 10.3 | Guide to Pharmacology |
| SST5 | SSR5 | Rat | Somatostatin | A | pKi | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
| SST2 | SSR2 | Rat | Somatostatin | A | pKi | 8.8 | 8.8 | 8.8 | Guide to Pharmacology |
| SST5 | SSR5 | Mouse | Somatostatin | A | pKi | 9.8 | 9.85 | 9.9 | Guide to Pharmacology |
| SST3 | SSR3 | Rat | Somatostatin | A | pKi | 9.1 | 9.1 | 9.1 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| SST3 | SSR3 | Mouse | Somatostatin | A | pIC50 | 10.2 | 10.2 | 10.2 | Guide to Pharmacology |
| SST2 | SSR2 | Mouse | Somatostatin | A | pIC50 | 9.0 | 9.25 | 9.5 | Guide to Pharmacology |
| SST2 | SSR2 | Human | Somatostatin | A | pEC50 | 8.64 | 8.64 | 8.64 | ChEMBL |
| MRGPRX2 | MRGX2 | Human | A orphans | A | pEC50 | 5.38 | 5.38 | 5.38 | Guide to Pharmacology |