CHEMBL271513


SMILES COc1ccccc1N1CCN(Cc2ccc(OCCF)cc2)CC1
InChIKey RLXWQKHLDFBDJH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 344.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.27 5.27 5.27 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.47 5.47 5.47 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.43 8.43 8.43 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.11 7.11 7.11 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database