CHEMBL282424


SMILES Fc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1
InChIKey OOKNJSVAHXTYKL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 310.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.48 8.48 8.48 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.62 6.62 6.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database