CHEMBL28321


SMILES COc1ccccc1N1CCN(Cc2ccn(-c3ccccc3)c2)CC1
InChIKey UPXJKNQVKALXKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 347.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pKi 8.0 8.0 8.0 ChEMBL
D2 DRD2 Green monkey Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.98 9.15 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database