CHEMBL3139393


SMILES CCCCCCNC[C@H]1CCc2ccc(O)cc2O1
InChIKey QNPXMHDZEWNMNS-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 263.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.24 8.27 8.3 ChEMBL
D1 DRD1 Human Dopamine A pKi 4.96 4.97 4.98 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.26 6.99 7.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.58 7.18 8.2 ChEMBL
D5 DRD5 Human Dopamine A pKi 4.56 5.06 5.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 10.3 10.3 10.3 ChEMBL