U101958
| SMILES | CC(Oc1cccnc1N(C1CCN(CC1)Cc1ccccc1)C)C |
| InChIKey | WFLHEXUTTRRXFJ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 339.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| D4 | DRD4 | Human | Dopamine | A | pKi | 8.9 | 8.9 | 8.9 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | Potency | 4.8 | 4.8 | 4.8 | ChEMBL |
| D4 | DRD4 | Human | Dopamine | A | pIC50 | 8.1 | 8.2 | 8.3 | ChEMBL |
| D3 | DRD3 | Human | Dopamine | A | pIC50 | 5.26 | 5.26 | 5.26 | ChEMBL |
| D2 | DRD2 | Human | Dopamine | A | pIC50 | 6.21 | 6.21 | 6.21 | ChEMBL |