CHEMBL287217


SMILES c1ccc(CN2CCC(n3cnc(-c4ccccc4)c3)CC2)cc1
InChIKey JCQGRHIIKSHVDZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 317.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.4 7.4 7.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.13 6.13 6.13 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database