urocortin 2


SMILES None
InChIKey PIXFIEBACLDPNF-SKCWXFKWSA-N
Sequence IVLSLDVPIGLLQILLEQARARAAREQATTNARILARV

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF1 CRFR1 Human Corticotropin-releasing factor B1 pKd 5.3 5.35 5.4 Guide to Pharmacology
CRF2 CRFR2 Human Corticotropin-releasing factor B1 pKd 8.5 8.55 8.6 Guide to Pharmacology
CRF2 CRFR2 Mouse Corticotropin-releasing factor B1 pKd 9.3 9.3 9.3 Guide to Pharmacology
CRF2 CRFR2 Rat Corticotropin-releasing factor B1 pKd 8.8 8.8 8.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF2 CRFR2 Mouse Corticotropin-releasing factor B1 pEC50 8.37 8.37 8.37 ChEMBL