CHEMBL291908


SMILES Cc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1
InChIKey GUUIENZLFCYGEL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 369.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.67 8.67 8.67 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.13 7.13 7.13 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 6.23 6.23 6.23 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database