CHEMBL293695


SMILES COc1cccc2c1CC[C@H]1CN(CCn3c(=O)[nH]c4c(OC)c(OC)ccc4c3=O)C[C@@H]21
InChIKey KQQGSWIVATVKRC-HNAYVOBHSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.17 9.17 9.17 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 8.15 8.15 8.15 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 9.18 9.18 9.18 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 10.4 10.4 10.4 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 8.9 8.9 8.9 ChEMBL
α1A ADA1A Human Adrenoceptors A pKd 9.45 9.45 9.45 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database