CHEMBL298166


SMILES Cc1cccc(C(=O)NCN2CCN(c3ccccc3Cl)CC2)c1
InChIKey ZVHOLIZEVQEFBP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 343.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.57 7.65 7.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.33 6.33 6.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.88 6.11 6.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.8 7.8 7.8 ChEMBL