CHEMBL298763


SMILES O=C(NCN1CCN(c2ccccc2Cl)CC1)c1ccccc1
InChIKey NZCZNMGSFLEVRM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 329.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.97 7.32 7.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.75 6.75 6.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.82 6.29 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 6.97 6.97 6.97 ChEMBL