CHEMBL302186


SMILES c1ccc(CN2CCC(NCc3csc(-c4ccccc4)n3)CC2)cc1
InChIKey LDOTVWGSWWUMAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.17 5.17 5.17 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.64 5.64 5.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.64 4.75 4.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database