CHEMBL3084529


SMILES NC(=O)[C@@]1(c2ccc(F)cn2)C[C@@H]2CC[C@H](C1)N2C(c1ccccc1Cl)c1ccccc1Cl
InChIKey BZGMTXHQYFWFDV-JSCPRHNGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 483.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.15 8.15 8.15 ChEMBL
δ OPRD Human Opioid A pKi 5.47 5.47 5.47 ChEMBL
κ OPRK Human Opioid A pKi 5.79 5.79 5.79 ChEMBL
μ OPRM Human Opioid A pKi 6.91 6.91 6.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.7 7.7 7.7 ChEMBL
μ OPRM Human Opioid A pEC50 6.13 6.13 6.13 ChEMBL