CHEMBL3087219


SMILES COC(=O)N1[C@H]2CC[C@@H]1C[C@@](O)(C#Cc1cccc(OC)c1)C2
InChIKey QTDNCWWHRMDXCC-HWWDLCQESA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 315.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.13 7.13 7.13 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.12 7.12 7.12 ChEMBL