GproteinDb

CHEMBL325255

Agent/drug
Bioactivity

CHEMBL325255

SMILES	Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)/C=C/c4ccc(C(F)(F)F)cc4)c3C#N)c2n1
InChIKey	HRMANULVIPULPC-OQLLNIDSSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	592.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

B₂	BKRB2	Guinea pig	Bradykinin	A	pKi	9.52	9.52	9.52	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

B₂	BKRB2	Guinea pig	Bradykinin	A	pIC50	8.92	9.22	9.52	ChEMBL
B₂	BKRB2	Guinea pig	Bradykinin	A	pEC50	7.25	7.25	7.25	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL325255

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.