CHEMBL3264747


SMILES O=C1[C@H]2O[C@@]34CC[C@@]5(OCOc6c(O)ccc7c6[C@@]3(CCN(CC3CC3)[C@@H]4C7)[C@H]25)N1c1ccccc1
InChIKey MWNDHOWKMXFYLQ-HRPGWMCCSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 486.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Mouse Opioid A pKi 8.34 8.34 8.34 ChEMBL
δ OPRD Mouse Opioid A pKi 9.27 9.27 9.27 ChEMBL
κ OPRK Guinea pig Opioid A pKi 8.77 8.77 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 9.01 9.21 9.41 ChEMBL
κ OPRK Human Opioid A pEC50 8.19 8.55 8.92 ChEMBL
μ OPRM Human Opioid A pEC50 8.05 8.48 8.92 ChEMBL