CHEMBL310599


SMILES CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2Cl)CC1
InChIKey LZZIGVORZVSTNT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 465.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 9.12 9.12 9.12 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 9.52 9.52 9.52 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.94 7.94 7.94 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.6 9.6 9.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database