CHEMBL3289949


SMILES O=S(=O)(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(OC(F)(F)F)cc1
InChIKey PXFNUVRXAKDHRD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 514.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database