CHEMBL329566


SMILES CN(C)C[C@H]1C[C@@H]2c3ccccc3Cc3ccccc3[C@H]2O1
InChIKey ACTVOFFLDWZANE-NSISKUIASA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 293.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pKi 7.16 7.16 7.16 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.89 7.89 7.89 ChEMBL
H1 HRH1 Human Histamine A pKi 9.27 9.32 9.37 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
D1 DRD1 Human Dopamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 9.03 9.03 9.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.6 8.6 8.6 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database