CHEMBL3126735


SMILES Fc1ccc(C(SCCNCCCc2ccccc2)c2ccc(F)cc2)cc1
InChIKey IWZNOFWARONDLD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 10
Molecular weight (Da) 397.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.55 7.55 7.55 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.64 6.64 6.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pIC50 5.7 5.7 5.7 ChEMBL