CHEMBL331240


SMILES CC(=O)Nc1ccc(N2CCN(C(=O)COc3ccc4[nH]cc(CCN)c4c3)CC2)cc1
InChIKey KVIJKSNSHKOAJQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 7
Molecular weight (Da) 435.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.48 8.48 8.48 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.55 8.72 8.85 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.87 6.99 7.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database