CHEMBL3304308


SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)N(C)C(=O)C2(C)c2ccccc2)CC1
InChIKey ITZLTUNYOOOFFZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 464.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.83 4.83 4.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.63 7.63 7.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database